drugset / Trial / NCT04991129
The Safety and Efficacy of Multiple-dose of WJ01024 in Subject With Advanced Cancer
Non-randomizedSequentialOpen-labelTreatment
Summary
A clinical study of WJ01024 in subjects with advanced cancer in China, to evaluate the safety, tolerability, PK and efficacy of WJ01024. This study includes a dose escalation part and a dose expansion part. Patients receive WJ01024 on Day 1 and Day 3 of each week, 4 weeks as a cycle, until disease progression, or intolerable toxicity , withdrawal of consent, or end of the study, whichever occurs first.
Timeline
- Start
- 2021-09-10
- Primary completion
- 2025-05-28
- Completion
- 2025-05-28
Outcome
Outcome not reported
Stopped (Business): “Due to a change in the development strategy, the sponsor decided to terminate the study on May 28, 2025”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | WJ01024 | Unknown | 5 mg | — |
| Subject | WJ01024 | Unknown | 10 mg | — |
| Subject | WJ01024 | Unknown | 40 mg | — |
| Subject | WJ01024 | Unknown | 50 mg | — |
| Subject | WJ01024 | Unknown | 60 mg | — |
| Subject | WJ01024 | Unknown | 80 mg | — |