drugset / Trial / NCT04991207
Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Bosentan
RandomizedSequentialOpen-labelTreatment
Summary
the purpose of this study is: * To assess the effect of BIA 5 1058 400 mg on the PK of bosentan. * To assess the effect of bosentan on the PK of BIA 5 1058
Timeline
- Start
- 2018-02-06
- Primary completion
- 2018-05-14
- Completion
- 2018-05-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bosentan | Other / unclassified | 125 mg | Oral |
| Subject | zamicastat | Small molecule | 400 mg | Oral |