drugset / Trial / NCT04994626

Ibrutinib Combined With Rituximab for Treatment of Relapsed Refractory MYD88 and CD79A/B (or CD79B Alone) DLBCL Who Have Received at Least Two Prior Therapies

NCT04994626 ↗

Phase 2 Unknown 20 enrolled Chinese Academy of Medical Sciences
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of Ibrutinib Combined With Rituximab in Relapsed Refractory MYD88 and CD79A/B (or CD79B Alone) DLBCL Who Have Received at Least Two Prior Therapies.

Timeline

Start
2021-10-01
Primary completion
2022-04-01
Completion
2025-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibrutinib Small molecule 560 mg Oral
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous