drugset / Trial / NCT04997707

The Effect of Balanced Anesthesia Regimen on Intraoperative Trans-cranial Motor Evoked Potential During Spine Surgeries:

NCT04997707 ↗

Phase 4 Completed 60 enrolled El-Sahel Teaching Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

transcranial motor evoked potentials (TcMEP) were proved to be useful during complicated spinal surgeries to prevent iatrogenic complications. The effect of anesthetic agents was comprehensively discussed in literature. The Investigators studied a new balanced anesthetic protocol using propofol and sevoflurane in addition to continuous fentanyl infusion in which they compared values and ratios of amplitudes and latencies of TcMEP waves at different time point.

Timeline

Start
2017-04-06
Primary completion
2020-03-05
Completion
2021-04-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Abbott Unknown 25 ug/kg Intravenous
Comparator Propofol Abbott Unknown 75 ug/kg Intravenous
Comparator Propofol Abbott Unknown 100 ug/kg Intravenous
Comparator Sevoflurane Inhalation Solution Unknown 0.7 % Inhaled
Comparator Sevoflurane Inhalation Solution Unknown 0.9 % Inhaled
Comparator Sevoflurane Inhalation Solution Unknown 1.1 % Inhaled

Indications

No indication recorded.