drugset / Trial / NCT04997707
The Effect of Balanced Anesthesia Regimen on Intraoperative Trans-cranial Motor Evoked Potential During Spine Surgeries:
RandomizedParallel-groupTriple-blindTreatment
Summary
transcranial motor evoked potentials (TcMEP) were proved to be useful during complicated spinal surgeries to prevent iatrogenic complications. The effect of anesthetic agents was comprehensively discussed in literature. The Investigators studied a new balanced anesthetic protocol using propofol and sevoflurane in addition to continuous fentanyl infusion in which they compared values and ratios of amplitudes and latencies of TcMEP waves at different time point.
Timeline
- Start
- 2017-04-06
- Primary completion
- 2020-03-05
- Completion
- 2021-04-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol Abbott | Unknown | 25 ug/kg | Intravenous |
| Comparator | Propofol Abbott | Unknown | 75 ug/kg | Intravenous |
| Comparator | Propofol Abbott | Unknown | 100 ug/kg | Intravenous |
| Comparator | Sevoflurane Inhalation Solution | Unknown | 0.7 % | Inhaled |
| Comparator | Sevoflurane Inhalation Solution | Unknown | 0.9 % | Inhaled |
| Comparator | Sevoflurane Inhalation Solution | Unknown | 1.1 % | Inhaled |
Indications
No indication recorded.