drugset / Trial / NCT04997967
Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis
RandomizedParallel-groupOpen-labelHealth-services research
Summary
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a lengthy and uncomfortable procedure that requires adequate sedation. Propofol is the commonly used sedative during ERCP. However, dose dependent cardiac and respiratory depression may occur. Hypotension usually occurs in severe cholangitis which necessitate the use of alternative sedative. The aim is to study the efficacy and safety of ketofol as a sedative during urgent ERCP for severe cholangitis.
Timeline
- Start
- 2020-07-01
- Primary completion
- 2021-08
- Completion
- 2021-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 2 mg/ml | — |
| Comparator | Propofol | Small molecule | 50 ug/kg | Intravenous |
| Comparator | Propofol | Small molecule | 0.5 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 8 mg/ml | Intravenous |
Indications
No indication recorded.