drugset / Trial / NCT04999098

Echinaforce COVID-19 Shedding Study

NCT04999098

RandomizedParallel-groupSingle-blindTreatment

Summary

Respiratory viruses pose a permanent threat to humans and society as demonstrated by the current Covid-19 pandemic. Novel drugs and vaccines provide a means for controlling illness. Infections and symptomatic presentation of illness may be reduced, but it remains to be determined to which extent viral shedding and transmission (e.g. by silent transmitters) can be controlled. Lack of such activity may result in continuing viral spread by assumed healthy but asymptomatic spreaders. Echinacea is an established and readily-accessible product with demonstrated in vitro antiviral activity (including coronaviruses). This study aims to estimate the potential of different Echinacea formulations (head-to-head) to reduce concentration infectivity and shedding of SARS-CoV-2 under in vivo conditions.

Timeline

Start
2021-11-15
Primary completion
2023-05-15
Completion
2023-08-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator ECHINACEA, UNSPECIFIED Traditional medicine (herbal / TCM) 2800 mg Oral
Comparator Echinaforce Forte tablets Unknown 2400 mg Oral
Comparator Echinaforce tincture Unknown 2800 mg Other

Indications