drugset / Trial / NCT05004064

Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma

NCT05004064

Phase 2 Active not recruiting 48 enrolled University College, London AstraZeneca · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II, single-arm, open-label, multicentre study of acalabrutinib and rituximab for elderly or frail patients with previously untreated mantle cell lymphoma.

Timeline

Start
2023-11-30
Primary completion
2026-06-08
Completion
2028-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Acalabrutinib Small molecule 100 mg Oral
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous

Indications