drugset / Trial / NCT05005806

Fish Oil (Omega 3 ) in Sjogren's Syndrome

NCT05005806

Phase 2/3 Completed 100 enrolled Hawler Medical University
RandomizedParallel-groupTriple-blindTreatment

Summary

Sjögren's syndrome (pSS) is an autoimmune disorder affecting mainly the exocrine glands.this lead to dryness of the main mucosal surface ,such as the mouth ,eye,skin nose,pharynx,larynx and vagina . The history of the disease is characterized by a slowly progression of sicca symptoms and fatigue; however, a subset of patients would experience extra glandular activity. Lipid mediators derived from polyunsaturated fatty acids, related to inflammation and immune response regulation. In this sense, the polyunsaturated fatty acids omega-3 (ω-3 FA) have been associated with several illnesses such as cancer, cardiovascular disease and autoimmune diseases and their balance at the cellular membranes can result in an anti-inflammatory .

Timeline

Start
2021-09-02
Primary completion
2023-02-01
Completion
2023-02-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lovaza Other / unclassified 1000 mg

Indications