drugset / Trial / NCT05006170
Pharmacokinetics, Safety, and Efficacy of Dolutegravir Dispersible Tablets in Young Children Living With HIV
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate steady-state pharmacokinetics of DTG dispersible tablets in children with HIV infection weighing from 6 to below 20 kg and to determine the dose of DTG that achieves adult target PK parameter(trough concentration; AUC24h)
Timeline
- Start
- 2021-08-03
- Primary completion
- 2022-02-28
- Completion
- 2022-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dolutegravir | Other / unclassified | 20 mg | Oral |
| Subject | Dolutegravir | Other / unclassified | 25 mg | Oral |