drugset / Trial / NCT05006716

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

NCT05006716 ↗

Phase 1/2 Recruiting 689 enrolled BeOne Medicines
RandomizedSingle-groupOpen-labelTreatment

Summary

Study consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts)

Timeline

Start
2021-09-13
Primary completion
2027-03
Completion
2030-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Tacabrutideg Unknown — Oral