drugset / Trial / NCT05013099

Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies

NCT05013099

Phase 2 Active not recruiting 70 enrolled ImaginAb, Inc.
NaSingle-groupOpen-labelDiagnostic

Summary

The purpose of this study is to evaluate whether zirconium Zr 89 crefmirlimab berdoxam (other names 89Zr-crefmirlimab berdoxam, 89Zr-Df-crefmirlimab, 89Zr-Df-IAB22M2C) PET/CT can predict the response of advanced or metastatic melanoma, Merkel cell carcinoma, renal cell carcinoma, or non-small cell lung cancer tumors to immuno-oncology therapy.

Timeline

Start
2021-12-09
Primary completion
2025-07
Completion
2025-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ⁸⁹Zr-Df-IAB22M2C Diagnostic / imaging agent 1.5 mg Intravenous
Subject ⁸⁹Zr-Df-IAB22M2C Diagnostic / imaging agent 37 mbq Intravenous