drugset / Trial / NCT05015881

Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder

NCT05015881 ↗

Phase 2/3 Enrolling by invitation 20 enrolled University of Pennsylvania
RandomizedCrossoverOpen-labelBasic science

Summary

The goal of this study is to learn more about how a nutritional supplement "ketone ester" (deltaG ®) has an effect on brain and heart function and on alcohol consumption in individuals with and without alcohol use disorder. The study will use Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) scans after a single dose of ketone ester or Placebo in 10 people with alcohol use disorder and 10 healthy control volunteers.

Timeline

Start
2021-11-01
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Background 2-Deoxy-2-[18F] fluoro-D-glucose (FDG) Diagnostic / imaging agent — Intravenous