drugset / Trial / NCT05020678

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

NCT05020678 ↗

Phase 1 Active not recruiting 150 enrolled Nkarta, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is a single arm, open-label, multi-center, Phase 1 study to determine the safety and tolerability of an experimental therapy called NKX019 (allogeneic CAR NK cells targeting CD19) in patients with relapsed/refractory non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL) or B cell acute lymphoblastic leukemia (B-ALL)

Timeline

Start
2021-08-20
Primary completion
2025-03-31
Completion
2038-12

Drugs

EvaluationDrugModalityDoseRoute
Subject NKX019 Cell therapy 6e+06 cells/kg Intravenous
Subject NKX019 Cell therapy 3e+08 cells Intravenous