drugset / Trial / NCT05021991

A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor

NCT05021991 ↗

Phase 2 Completed 133 enrolled Praxis Precision Medicines
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This multi-center, randomized, double-blinded, placebo-controlled, dose-range-finding clinical trial (with an optional Extension comprised of an Extension Double-blind (DB) Lead in Period followed by an Extension Open-label (OL) Period) that will assess the efficacy, safety, and tolerability of PRAX 944 in participants aged 18 years or older who have a diagnosis of Essential Tremor (ET) and have had symptoms for at least 3 years.

Timeline

Start
2021-10-14
Primary completion
2023-02-09
Completion
2024-02-29

Drugs

EvaluationDrugModalityDoseRoute
Subject ulixacaltamide Small molecule 20 mg Oral
Subject ulixacaltamide Small molecule 60 mg Oral
Subject ulixacaltamide Small molecule 100 mg Oral

Indications