Alpha-Bisabolol Gel With Antihistamine Action
Summary
It will be developed and evaluated the antihistamine potential of a gel containing alpha-bisabolol. Method: Interventional and cross-sectional study, with convenience sampling, conducted with 20 volunteers. The forearm will be sensitized at four points (A, B, C and D). Point A: positive control will be sensitized with a drop of histamine at a concentration of 10 mg / Ml. Point B: histamine will apply and immediately after, the alpha bisabolol gel with a concentration of 0.5%. Point C: histamine and gel with 2.5% alpha-bisabolol will apply. Point D will be sensitized with a drop of histamine and 5.0% alpha-bisabolol gel. The test reading at each point will occur 15 minutes after the procedure. For the analysis of the results, the T Test will be applied.
Timeline
- Start
- 2020-04-01
- Primary completion
- 2020-08-01
- Completion
- 2020-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alpha bisabolol | Small molecule | 0.5 % | Topical |
| Subject | Alpha bisabolol | Small molecule | 2.5 % | Topical |
| Subject | Alpha bisabolol | Small molecule | 5 % | Topical |
Indications
No indication recorded.