drugset / Trial / NCT05022628

Clinical Study of Radiotherapy Combined With Donafenib for Neoadjuvant Treatment of Patients With HCC With Portal Vein Carcinoma Thrombosis

NCT05022628

Phase 4 Unknown 30 enrolled Anhui Provincial Hospital
NaSingle-groupOpen-labelTreatment

Summary

For HCC patients with combined PVTT, systemic therapy can be used as a basic approach throughout the treatment and in combination with hepatectomy, TACE, HAIC, radiotherapy, etc. Our center proposes to conduct a clinical study of radiotherapy combined with donafinil for neoadjuvant treatment of HCC patients with portal vein carcinoma thrombosis to observe the safety and efficacy of donafinib combined with radiotherapy for neoadjuvant treatment Translated with www.DeepL.com/Translator (free version)

Timeline

Start
2021-09-30
Primary completion
2023-08
Completion
2024-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Donafenib Small molecule 0.2 g Oral