Transmucular Quadratus Lumborum Block: Potential Quadriceps Muscle Weakness

Phase 4 Completed 20 enrolled Zealand University Hospital

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The aim of this study is to examine whether the administration of the TQL block cause motor block of the lumbar plexus and thereby quadriceps muscle weakness. The investigators hypothesise that the administration of a unilateral TQL block does not cause quadriceps muscle weakness compared to a placebo block.

Timeline

Start: 2021-10-02
Primary completion: 2021-11-28
Completion: 2021-11-28

Publications

Tanggaard K, Nielsen MV, Holm UHU, Hoffmann BM, Bernhoff C, Andersen CH, Thomassen SS, Hansen C, Dam M, Poulsen TD, Holm PM, Borglum J. No quadriceps muscle weakness following anterior quadratus lumborum block compared with placebo: a randomized, non-inferiority, blinded, volunteer trial. Reg Anesth Pain Med. 2025 Jul 4;50(7):568-574. doi: 10.1136/rapm-2024-105313.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ropivacaine	Other / unclassified	0.75 %	Other
Comparator	Ropivacaine	Other / unclassified	30 ml	Other

Indications

No indication recorded.