drugset / Trial / NCT05027139

A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer

NCT05027139

Phase 1/2 Completed 52 enrolled Jazz Pharmaceuticals ALX Oncology Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is being done to find out if zanidatamab when given with evorpacept (ALX148) is safe and can treat patients with advanced (locally advanced \[inoperable\] and/or metastatic) human epidermal growth factor receptor 2 (HER2)-expressing cancer.

Timeline

Start
2021-09-15
Primary completion
2025-08-29
Completion
2025-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Evorpacept Protein / enzyme biologic Intravenous
Subject Zanidatamab Monoclonal antibody Intravenous

Indications