drugset / Trial / NCT05028374

COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies

NCT05028374

Phase 2 Completed 119 enrolled Barbara Ann Karmanos Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

To determine whether protective antibody levels increase after booster dosing with the Moderna COVID-19 vaccine in patients diagnosed with Hematologic Malignancies who have low antibody levels after a prior first vaccination with any of the SARS-CoV2 vaccines that were authorized for use in the USA. Researchers will also assess whether the booster dosing with the Moderna COVID-19 vaccine is safe in patients with multiple myeloma, amyloidosis, or other blood cancers.

Timeline

Start
2021-08-17
Primary completion
2021-11-02
Completion
2021-11-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Moderna mRNA COVID-19 vaccine Vaccine 0.5 ml Intramuscular