drugset / Trial / NCT05030298

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

NCT05030298

Phase 1 Recruiting 28 enrolled Mayo Clinic
NaSequentialOpen-labelTreatment

Summary

This phase I trial finds out the possible benefits and/or side effects of radiosurgery before surgery (preoperative) in treating patients with high grade glioma. Radiosurgery uses special equipment to position the patient and precisely give a single large dose of radiation to the tumor. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Giving pre-operative radiosurgery may improve the odds of brain tumor control and reduce treatment-related side effects.

Timeline

Start
2023-05-23
Primary completion
2027-09-15
Completion
2027-09-15

Drugs

EvaluationDrugModalityDoseRoute
Background Temozolomide Small molecule

Indications