drugset / Trial / NCT05030675

Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents

NCT05030675

NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is to find out the best dose, possible benefits and/or side effects of fostamatinib in treating patients with lower-risk myelodysplastic syndromes or chronic myelomonocytic leukemia who have failed therapy with hypomethylating agents. Fostamatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2021-08-13
Primary completion
2024-08-08
Completion
2024-08-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Fostamatinib Small molecule Oral