drugset / Trial / NCT05030857
Drug-drug Interaction and Food-effect Study With GLPG4716 and Midazolam in Healthy Subjects
NaSingle-groupOpen-labelBasic science
Summary
The purpose of this study is to determine the effect of the administration of multiple doses of GLPG4716 on the amount of midazolam (MDZ) that gets into the blood when the two drugs are administered together compared to when midazolam is administered alone. Other objectives of this study are to evaluate the safety and tolerability of GLPG4716 when administered with midazolam and assess the amount of GLPG4716 that gets into the blood when administered with midazolam. This study will also assess the effect of food on the amount of GLPG4716 that gets into the blood.
Timeline
- Start
- 2021-09-08
- Primary completion
- 2021-11-13
- Completion
- 2021-11-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | Small molecule | — | Oral |
| Subject | Midazolam | Small molecule | — | Oral |
Indications
No indication recorded.