The Treatment of Bioartificial Liver With hiHep Cells After Extensive Hepatectomy

Summary

It is a prospective, non-randomized, single-arm cohort study. A total of 10 patients will be included in this study. Based on standardized treatment, the treatment of bioartificial liver device will be applied 48-72 hours after extensive hepatectomy. The bioartificial liver device consists of clinical-grade human-induced hepatocytes (hiHep) generated from human fibroblasts via transdifferentiation. In order to evaluate the security and effectiveness of the device, liver function, liver volume, the incidence of liver failure and other results will be analyzed.

Timeline

Start

2021-09-05

Primary completion

2030-11-30

Completion

2030-11-30

Drugs

Indications