68Ga-FAPI PET/MR for Atherosclerosis

Summary

A thin-cap fibroatheroma with a large necrotic core and macrophage infiltration marks the vulnerable plaque. Fibroblast activating protein (FAP) is an active serine protease, which can degrade type I collagen, potentially thinning the fibrous cap. Thus we speculate that atherosclerotic plaque could be imaged with 68Ga-FAPI PET/MR.

Timeline

Start

2021-05-26

Primary completion

2023-08-30

Completion

2023-08-30

Drugs

Indications