Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude

Summary

Sleep at altitude is often poor. The purpose of this study is to evaluate the effects of a single dose of the opioid antagonist, naltrexone, on sleep quality and periodic breathing after rapid ascent to \~3800m altitude.

Timeline

Start

2021-08-08

Primary completion

2021-10-17

Completion

2021-10-17

Publications

• Foster K, Anholm JD, Foster G, Thapamagar S, Subedi P. Effects of Naltrexone on Sleep Quality and Periodic Breathing at High Altitude. High Alt Med Biol. 2025 Mar;26(1):13-19. doi: 10.1089/ham.2024.0023. Epub 2024 Jul 5.

Drugs

Indications