Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

Summary

1. This is an prospective study to evaluate the effect of gene polymorphisms on therapeutic responses to glucagon like peptide-1 receptor agonist (GLP-1 RA) in patients with T2DM. 2. T2DM patients and healthy subjects were recruited to identify genotypes and detect the level of T2DM susceptibility genes expression levels in the plasma of healthy participants and T2DM patients. 3. This is a retrospective cohort study of patients with T2DM who were treated with exenatide twice daily as a part of their diabetes care for at least 12 months.

Timeline

Start

2019-01-10

Primary completion

2023-10-01

Completion

2024-01-02

Drugs

Indications