drugset / Trial / NCT05037617
The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With Induction
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This pilot project is a randomized controlled trial where induced patients receive an intervention of oxytocin discontinuation once in the active stage of labor (≥6 cm dilation). The intent is to reduce uterine hyperstimulation and fetal distress, therefore, lowering cesarean sections (CS) in first time mothers at term (≥ 37 weeks), with a cephalic presenting singleton fetus, without increasing maternal or neonatal morbidity. If REDUCE-I pilot trial suggests a safe reduction in CS rates and patient satisfaction, application for a multi-centre randomized controlled trial would follow.
Timeline
- Start
- 2021-10-25
- Primary completion
- 2024-02-15
- Completion
- 2024-02-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxytocin | Peptide | — | — |
Indications
No indication recorded.