drugset / Trial / NCT05037617

The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With Induction

NCT05037617 ↗

Completed 205 enrolled University of Calgary
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This pilot project is a randomized controlled trial where induced patients receive an intervention of oxytocin discontinuation once in the active stage of labor (≥6 cm dilation). The intent is to reduce uterine hyperstimulation and fetal distress, therefore, lowering cesarean sections (CS) in first time mothers at term (≥ 37 weeks), with a cephalic presenting singleton fetus, without increasing maternal or neonatal morbidity. If REDUCE-I pilot trial suggests a safe reduction in CS rates and patient satisfaction, application for a multi-centre randomized controlled trial would follow.

Timeline

Start
2021-10-25
Primary completion
2024-02-15
Completion
2024-02-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxytocin Peptide — —

Indications

No indication recorded.