drugset / Trial / NCT05045950
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
NaSingle-groupOpen-labelTreatment
Summary
Study patients will receive Whole-brain radiation therapy (WBRT) - pulsed reduced dose rate (PRDR) within 14 days of registration. All patients will receive single daily fractions using 3D conformal radiotherapy. A dose of 30 Gy in 10 fractions will be delivered using the PRDR technique.
Timeline
- Start
- 2021-11-17
- Primary completion
- 2028-05
- Completion
- 2029-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Memantine | Unknown | 20 mg | Oral |
| Background | Memantine | Unknown | 28 mg | Oral |