drugset / Trial / NCT05047510

GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma

NCT05047510 ↗

Recruiting 60 enrolled Chinese Academy of Sciences
NaSingle-groupOpen-labelDiagnostic

Summary

This study is to evaluate whether intraoperative fluorescence imaging targeting GPC3 can aid improve the surgical accuracy of hepatocellular carcinoma. The main purposes of this study include: ① To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the GPC-3 targeted fluorophore. ② To validate the safety and effectiveness of the designed GPC-3 targeted fluorophore for clinical application.

Timeline

Start
2021-09-10
Primary completion
2025-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Anti-GPC3-IRDye800CW Unknown — Other