drugset / Trial / NCT05048940

Efficacy, Safety, and Immunogenicity of Vaccine Reimmunization With a Third Homologous Versus Heterologous Dose Against COVID-19 in Patients Undergoing Solid Organ Transplantation.

NCT05048940

RandomizedParallel-groupOpen-labelPrevention

Summary

Patients undergoing solid organ transplantation randomly selected from those who have received two doses of Spikevax (Moderna) vaccine, provided that a minimum of 8 weeks have elapsed from the second dose to the time of the start of the trial. It is planned to include 386 patients.

Timeline

Start
2021-09-01
Primary completion
2021-09-01
Completion
2021-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject COVID-19 Vaccine Janssen Vaccine 0.5 ml Intramuscular
Comparator Elasomeran Messenger RNA (mRNA) 0.5 ml Intramuscular

Indications