A Trial to Evaluate the Effect of Delgocitinib on the Heart Rhythm of Healthy People

Phase 0 Completed 40 enrolled LEO Pharma

RandomizedParallel-groupTriple-blindOther

Summary

The purpose of this trial is to investigate the effects of delgocitinib, taken as a capsule, on the heart rhythms of healthy people, compared to a placebo.

Timeline

Start: 2021-09-29
Primary completion: 2022-01-04
Completion: 2022-01-04

Publications

Thaci D, Gooderham M, Lovato P, Madsen DE, Soehoel A, Bissonnette R. Systemic exposure and bioavailability of delgocitinib cream in adults with moderate to severe Chronic Hand Eczema. J Eur Acad Dermatol Venereol. 2025 Sep;39(9):1612-1621. doi: 10.1111/jdv.20777. Epub 2025 Jun 17.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Delgocitinib	Small molecule	—	Oral

Indications

No indication recorded.