drugset / Trial / NCT05052554

Study With QR-504a to Evaluate Safety, Tolerability & Corneal Endothelium Molecular Biomarker(s) in Subjects With FECD3

NCT05052554 ↗

Phase 1 Withdrawn ProQR Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

PQ-504a-001 (Fuchs Focus) is an open-label, single-dose, exploratory study to evaluate safety, tolerability, and corneal endothelium molecular biomarker(s) in subjects with Fuchs Endothelial Corneal Dystrophy with Trinucleotide Repeat Expansion in the TCF4 gene (FECD3).

Timeline

Start
2021-08-10
Primary completion
2022-04-12
Completion
2022-04-12

Outcome

Outcome not reported

Stopped: “No patients”

Drugs

EvaluationDrugModalityDoseRoute
Subject QR-504a Unknown 30 ug Intravitreal
Subject QR-504a Unknown 60 ug Intravitreal