drugset / Trial / NCT05054543

Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML

NCT05054543

Phase 3 Terminated 140 enrolled Apollomics Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This bridging study will evaluate the efficacy of uproleselan, a specific E-selectin antagonist, in combination with chemotherapy to treat Chinese relapsed/refractory AML patients, compared to chemotherapy alone. The safety of uproleselan when given with chemotherapy will also be investigated in patients with relapsed/refractory AML

Timeline

Start
2021-11-17
Primary completion
2024-08-22
Completion
2024-08-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Uproleselan Small molecule