drugset / Trial / NCT05057481

Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus

NCT05057481

Phase 3 Unknown 30 enrolled Assiut University
RandomizedParallel-groupOpen-labelTreatment

Summary

There is a deficiency in guidelines about the treatment of autoimmune hemolytic anemia in systemic lupus erythematosus (SLE), especially in refractory cases. Mycophenolate mofetil (MMF) showed promising results in those patients but still, the data available are in form of case reports. So, investigators will investigate the efficiency of MMF against a well-established treatment Rituximab in the treatment of refractory autoimmune hemolytic anemia in SLE patients.

Timeline

Start
2021-09-15
Primary completion
2022-12-31
Completion
2023-01-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mycophenolate Mofetil Small molecule 2 g Oral
Comparator Rituximab Monoclonal antibody 375 mg/m2 Intravenous