drugset / Trial / NCT05057481
Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus
RandomizedParallel-groupOpen-labelTreatment
Summary
There is a deficiency in guidelines about the treatment of autoimmune hemolytic anemia in systemic lupus erythematosus (SLE), especially in refractory cases. Mycophenolate mofetil (MMF) showed promising results in those patients but still, the data available are in form of case reports. So, investigators will investigate the efficiency of MMF against a well-established treatment Rituximab in the treatment of refractory autoimmune hemolytic anemia in SLE patients.
Timeline
- Start
- 2021-09-15
- Primary completion
- 2022-12-31
- Completion
- 2023-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Mycophenolate Mofetil | Small molecule | 2 g | Oral |
| Comparator | Rituximab | Monoclonal antibody | 375 mg/m2 | Intravenous |