drugset / Trial / NCT05057715

huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer

NCT05057715

Phase 1 Active not recruiting 13 enrolled University of Pennsylvania Theriva Biologics SL · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a single-center phase 1 study to evaluate the safety and feasibility of huCART-meso cells given in combination with VCN-01 in patients with unresectable or metastatic pancreatic adenocarcinoma and serous epithelial ovarian cancer.

Timeline

Start
2022-03-02
Primary completion
2038-09
Completion
2038-09

Drugs

EvaluationDrugModalityDoseRoute
Subject huCART-meso Cell therapy 5e+07 cells Intravenous
Subject zabilugene almadenorepvec Unknown 3.3e+12 unknown Intravenous
Subject zabilugene almadenorepvec Unknown 1e+13 unknown Intravenous