drugset / Trial / NCT05061524
A FIH Study of YH35324 in Atopic Healthy Subjects or Subjects with Mild Allergic Diseases
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to evaluate the safety, tolerability, PK, and PD following subcutaneous injections of YH35324 in atopic healthy subjects or adult subjects with mild allergic diseases. Eligible subjects will be randomized to the YH35324 group, the placebo group, or the omalizumab group.
Timeline
- Start
- 2021-09-26
- Primary completion
- 2023-01-25
- Completion
- 2023-01-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Omalizumab | Monoclonal antibody | 300 mg | Subcutaneous |
| Subject | YH35324 | Unknown | 0.3 mg/kg | Subcutaneous |
| Subject | YH35324 | Unknown | 1 mg/kg | Subcutaneous |
| Subject | YH35324 | Unknown | 3 mg/kg | Subcutaneous |
| Subject | YH35324 | Unknown | 6 mg/kg | Subcutaneous |
| Subject | YH35324 | Unknown | 9 mg/kg | Subcutaneous |