A Study to Test the Efficacy, Safety and Tolerability of Romosozumab Treatment in Postmenopausal Chinese Women With Osteoporosis

Summary

The purpose of the study is to evaluate the effect of treatment with romosozumab for 6 months compared with placebo on the percent changes in bone mineral density (BMD) at the lumbar spine, at the total hip and femoral neck in postmenopausal Chinese women with osteoporosis.

Timeline

Start

2021-10-21

Primary completion

2023-11-09

Completion

2023-11-09

Publications

• Zhenlin Z, Qingyun X, Decai C, Aijun C, Yanan H, Mei Z, Xu C, Hua L, Youjia X, Qun C, Huilin Y, Xiaoyan X, Yujie L, Xuan D, Jun J, LingLing G, Theresa RJ, Lars B, Weibo X. Romosozumab increases bone mineral density in postmenopausal Chinese women with osteoporosis: A randomised phase three study. J Orthop Translat. 2026 Jun 3;59:101135. doi: 10.1016/j.jot.2026.101135. eCollection 2026 Jul.

Drugs

Indications