Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy

Summary

Perioperative blockage of beta-adrenoreceptors is widely used in cardiac and non-cardiac surgery to reduce the rate of cardiovascular complications. Several randomized-controlled studies and meta-analysis showed that esmolol reduces the incidence of myocardial ischemia and arrhythmias in cardiac surgery as well as enhances postoperative cardiac performance. No studies assessed the influence of esmolol in patients with hypertrophic obstructive cardiomyopathy undergoing cardiac surgery.

Timeline

Start

2021-10-06

Primary completion

2023-06-01

Completion

2023-07-01

Drugs

Indications