drugset / Trial / NCT05076396

PM14 Administered Intravenously to Patients With Advanced Solid Tumors

NCT05076396 ↗

Phase 1 Completed 126 enrolled PharmaMar
NaSingle-groupOpen-labelTreatment

Summary

Despite recent advances in the treatment of solid tumors in general, advanced (metastatic) disease remains mostly incurable and there is an urgent need to develop new therapeutic options for these patients, particularly investigational drugs with novel mechanisms of action. The investigation of new combination regimens of non-crossresistant agents with acceptable-and not completely overlapping-toxicities has been a major way to improve response rate and outcome of patients with advanced solid tumors.

Timeline

Start
2017-09-06
Primary completion
2025-08-21
Completion
2025-08-21

Drugs

EvaluationDrugModalityDoseRoute
Subject PM14 Unknown 0.25 mg/m2 Intravenous
Subject PM14 Unknown 4.5 mg/m2 Intravenous