drugset

drugset / Trial / NCT05076942

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III

NCT05076942 ↗

Phase 2 Recruiting 157 enrolled University Medical Center Groningen Dutch Cancer Society · collab NRG Oncology · collab

NaSingle-groupOpen-labelTreatment

Summary

Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.

Timeline

Start: 2021-01-01
Primary completion: 2028-01-01
Completion: 2029-01-01

Publications

Gien LT, Slomovitz B, Van der Zee A, Oonk M. Phase II activity trial of high-dose radiation and chemosensitization in patients with macrometastatic lymph node spread after sentinel node biopsy in vulvar cancer: GROningen INternational Study on Sentinel nodes in Vulvar cancer III (GROINSS-V III/NRG-GY024). Int J Gynecol Cancer. 2023 Apr 3;33(4):619-622. doi: 10.1136/ijgc-2022-004122.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cisplatin	Other / unclassified	40 mg/m2	Intravenous

Indications