Ropivacaine and Midazolam by Intraarticular vs Epidural Administration in Arthroscopic ACL

Summary

Compare of the effectiveness of the use of ropivacaine and midazolam by intraarticular vs epidural administration on post-operative analgesia after isolated arthroscopic anterior cruciate ligament (ACL) reconstruction with hamstring autograft.

Timeline

Start

2019-01-31

Primary completion

2021-01-31

Completion

2021-02-05

Publications

• Results Baldawi M, McKelvey G, Saasouh W, Perov S, Mostafa G, Saleh K. A Comparison of Neuraxial and General Anesthesia for Thirty-Day Postoperative Outcomes in United States Veterans Undergoing Total Knee Arthroplasty. J Arthroplasty. 2020 Nov;35(11):3138-3144. doi: 10.1016/j.arth.2020.06.030. Epub 2020 Jun 17.
• Results Baverel L, Cucurulo T, Lutz C, Colombet, Cournapeau J, Dalmay F, Lefevre N, Letartre R, Potel JF, Roussignol X, Surdeau L, Servien E; French Arthroscopic Society. Anesthesia and analgesia methods for outpatient anterior cruciate ligament reconstruction. Orthop Traumatol Surg Res. 2016 Dec;102(8S):S251-S255. doi: 10.1016/j.otsr.2016.08.007. Epub 2016 Sep 26.
• Results Dauri M, Polzoni M, Fabbi E, Sidiropoulou T, Servetti S, Coniglione F, Mariani P, Sabato AF. Comparison of epidural, continuous femoral block and intraarticular analgesia after anterior cruciate ligament reconstruction. Acta Anaesthesiol Scand. 2003 Jan;47(1):20-5. doi: 10.1034/j.1399-6576.2003.470104.x.
• Results Hong AJ, Agarwalla A, Liu JN, Gowd AK, McMillan S, Sethi PM, Amin NH. Neurological structures and mediators of pain sensation in anterior cruciate ligament reconstruction. Ann Anat. 2019 Sep;225:28-32. doi: 10.1016/j.aanat.2019.05.010. Epub 2019 Jun 11.
• Results Johnson RL, Kopp SL, Burkle CM, Duncan CM, Jacob AK, Erwin PJ, Murad MH, Mantilla CB. Neuraxial vs general anaesthesia for total hip and total knee arthroplasty: a systematic review of comparative-effectiveness research. Br J Anaesth. 2016 Feb;116(2):163-76. doi: 10.1093/bja/aev455.
• Results Lauretti GR, de Oliveira R, Perez MV, Paccola CA. Postoperative analgesia by intraarticular and epidural neostigmine following knee surgery. J Clin Anesth. 2000 Sep;12(6):444-8. doi: 10.1016/s0952-8180(00)00189-6.
• Results Nahravani M, Tekye SM, Alipour M, Makhmalbaf H, Aghaee MA. Analgesia Following Arthroscopy - a Comparison of Intra-articular Bupivacaine and/or Midazolam and or Fentanyl. Arch Bone Jt Surg. 2017 Jan;5(1):28-31.
• Results Padwal JA, Burton BN, Fiallo AA, Swisher MW, Gabriel RA. The association of neuraxial versus general anesthesia with inpatient admission following arthroscopic knee surgery. J Clin Anesth. 2019 Sep;56:145-150. doi: 10.1016/j.jclinane.2019.01.045. Epub 2019 Feb 23.
• Results Parker RD, Streem K, Schmitz L, Martineau PA; Marguerite Group. Efficacy of continuous intra-articular bupivacaine infusion for postoperative analgesia after anterior cruciate ligament reconstruction: a double-blinded, placebo-controlled, prospective, and randomized study. Am J Sports Med. 2007 Apr;35(4):531-6. doi: 10.1177/0363546506296313. Epub 2007 Jan 23.
• Results Peng K, Chen WR, Meng XW, Zhang J, Ji FH. Intra-articular dexmedetomidine in knee arthroscopy: A systematic review and meta-analysis. Sci Rep. 2018 Mar 6;8(1):4089. doi: 10.1038/s41598-018-22482-8.
• Results Zhou Y, Yang TB, Wei J, Zeng C, Li H, Yang T, Lei GH. Single-dose intra-articular ropivacaine after arthroscopic knee surgery decreases post-operative pain without increasing side effects: a systematic review and meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2016 May;24(5):1651-9. doi: 10.1007/s00167-015-3656-y. Epub 2015 Jun 7.
• Results Zou Z, An MM, Xie Q, Chen XY, Zhang H, Liu GJ, Shi XY. Single dose intra-articular morphine for pain control after knee arthroscopy. Cochrane Database Syst Rev. 2016 May 3;2016(5):CD008918. doi: 10.1002/14651858.CD008918.pub2.

Drugs

Indications

No indication recorded.