drugset / Trial / NCT05078931

A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

NCT05078931 ↗

Phase 2 Active not recruiting 35 enrolled Shanghai Chest Hospital Merck Sharp & Dohme LLC · collab
NaSingle-groupOpen-labelTreatment

Summary

This study will investigate the efficacy and safety of the combination of pembrolizumab and lenvatinib in PD-L1 positive patients with TKI-resistant EGFR-mutated advanced NSCLC.

Timeline

Start
2021-10-27
Primary completion
2025-12-30
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenvatinib Small molecule 20 mg Oral
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous