drugset

drugset / Trial / NCT05079789

Amiloride in Nephrotic Syndrome

NCT05079789 ↗

Phase 3 Terminated 20 enrolled University Hospital Tuebingen

RandomizedParallel-groupOpen-labelTreatment

Summary

The AMILOR study compares treatment of edema in nephrotic syndrome with Amiloride vs. Furosemide.

Timeline

Start: 2020-06-08
Primary completion: 2022-11-05
Completion: 2022-11-20

Publications

Background Artunc F, Worn M, Schork A, Bohnert BN. Proteasuria-The impact of active urinary proteases on sodium retention in nephrotic syndrome. Acta Physiol (Oxf). 2019 Apr;225(4):e13249. doi: 10.1111/apha.13249. Epub 2019 Jan 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Amiloride	Small molecule	5 mg	—
Comparator	Furosemide	Other / unclassified	40 mg	—

Indications