drugset / Trial / NCT05088642

A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects

NCT05088642

Phase 1 Completed 24 enrolled Jiangsu HengRui Medicine Co., Ltd.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a single-dose, open-label, phase I clinical study evaluating the PK of hetrombopag in subjects with mild hepatic impairment (Child-Pugh Class A), subjects with moderate hepatic impairment (Child-Pugh Class B), as well as age-, weight-, and gender-matched subjects with normal hepatic function.

Timeline

Start
2020-09-28
Primary completion
2020-12-04
Completion
2020-12-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Hetrombopag Small molecule

Indications