AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation

Summary

The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulgaris with risk of acne-induced post inflammatory hyperpigmentation (PIH) after 24 weeks of treatment in facial acne participants

Timeline

Start

2021-12-22

Primary completion

2022-12-15

Completion

2022-12-15

Publications

• Dias-Barbosa C, Taylor N, Chan K, York JP, Puelles J, Chavda R. Patient Insights on Acne Hyperpigmentation, Trifarotene, and Skincare: 6-Month, LEAP Phase 4 Qualitative Exit Interview Findings. Patient. 2026 Mar;19(2):343-352. doi: 10.1007/s40271-025-00789-9. Epub 2025 Nov 24.

Drugs

Indications