drugset / Trial / NCT05091320

Mechanical Thrombectomy of Medium Sized Vessels "M2 of MCA".

NCT05091320

Phase 3 Unknown 60 enrolled Assiut University
Non-randomizedParallel-groupSingle-blindTreatment

Summary

Mechanical thrombectomy recently has revolutionized the treatment of stroke. Trials have demonstrated the superiority of mechanical thrombectomy in large vessel occlusions, such as in the intracranialinternal carotid artery and proximal, middle cerebral artery (M1), middle cerebral artery trunk (M1), have relatively high rates of revascularization and favorable clinical outcomes after MT. , However second-order branches of the middle cerebral artery (M2) occlusions (postbifurcation in the Sylvian fissure) were underrepresented or not represented in the trials. Posing a more significant technical challenge to the available endovascular devices because of the smaller size and tortuosity of these arteries and the greater likelihood of recanalization with intravenous thrombolysis, the overall risk-benefit remains uncertain.

Timeline

Start
2021-12-01
Primary completion
2022-11-30
Completion
2022-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Alteplase Protein / enzyme biologic Intravenous

Indications