drugset / Trial / NCT05093335

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

NCT05093335

Phase 0 Recruiting 30 enrolled Memorial Sloan Kettering Cancer Center
NaSingle-groupOpen-labelDiagnostic

Summary

The purpose of this study is to determine the uptake of the imaging agent \[68Ga\]-pentixafor with PET/CT scans in people with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and non-Hodgkin lymphoma (NHL), or you have histiocytic neoplasms (Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD) and/or Rosai-Dorfman disease (RDD).

Timeline

Start
2021-10-01
Primary completion
2027-10
Completion
2027-10

Drugs

EvaluationDrugModalityDoseRoute
Subject 68Ga-Pentixafor Peptide 111 mbq Intravenous
Subject 68Ga-Pentixafor Peptide 185 mbq Intravenous