drugset / Trial / NCT05097378
Perioperative Encobini in BRAFV600 Mutant Stage III (B/C/D) or Oligometastatic Stage IV Melanoma
RandomizedParallel-groupOpen-labelTreatment
Summary
A two-arm, randomised trial investigating the response of encorafenib and binimetinib compared to standard adjuvant therapy.
Timeline
- Start
- 2022-01-01
- Primary completion
- 2023-09-01
- Completion
- 2024-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Binimetinib | Small molecule | 45 mg | Oral |
| Subject | Encorafenib | Small molecule | 450 mg | Oral |