drugset / Trial / NCT05098704
Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk
Phase 2/3
Recruiting
90 enrolled
University Hospital, Bordeaux
Ministry for Health and Solidarity, France · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Systemic sclerosis (SSc) is a severe autoimmune disease associating dysimmunity, vasculopathy and fibrosis. No curative treatment is available. Pre-clinical abnormalities can be found such as specific autoantibodies. The association of Raynaud phenomenon and SSc-specific anti-nuclear antibodies is the hallmark of pre-scleroderma subjects, among who around 47% declare a complete disease after five years. The aim of this study is to assess in this particular population the preventive effect of an anti-platelet treatment.
Timeline
- Start
- 2022-06-22
- Primary completion
- 2032-06
- Completion
- 2032-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clopidogrel | Small molecule | 75 mg | — |