drugset / Trial / NCT05098704

Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk

NCT05098704

RandomizedParallel-groupTriple-blindTreatment

Summary

Systemic sclerosis (SSc) is a severe autoimmune disease associating dysimmunity, vasculopathy and fibrosis. No curative treatment is available. Pre-clinical abnormalities can be found such as specific autoantibodies. The association of Raynaud phenomenon and SSc-specific anti-nuclear antibodies is the hallmark of pre-scleroderma subjects, among who around 47% declare a complete disease after five years. The aim of this study is to assess in this particular population the preventive effect of an anti-platelet treatment.

Timeline

Start
2022-06-22
Primary completion
2032-06
Completion
2032-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Clopidogrel Small molecule 75 mg

Indications