drugset / Trial / NCT05101122

Study for Efficacy and Dose Escalation of AD313 + Atomoxetine (SEED)

NCT05101122

Phase 1/2 Completed 15 enrolled Apnimed
Non-randomizedSequentialOpen-labelTreatment

Summary

The SEED study is designed to assess the safety and efficacy for Obstructive Sleep Apnea (OSA) of 3 escalating dose combinations of atomoxetine with AD313 compared to baseline and to atomoxetine alone.

Timeline

Start
2021-10-19
Primary completion
2022-04-18
Completion
2022-04-18

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atomoxetine Other / unclassified 40 mg Oral
Comparator Atomoxetine Other / unclassified 80 mg Oral
Subject Dronabinol Other / unclassified 2.5 mg Oral
Subject Dronabinol Other / unclassified 5 mg Oral
Subject Dronabinol Other / unclassified 10 mg Oral